Acupunct Search

CLOSE


J Acupunct Res > Volume 33(1); 2016 > Article
Yoon, Hyeong, Hyun, Jae, Min, Won, and Woo: A Case Report of a Right-sided Hemichorea Patient Diagnosed with Chorea Hyperglycemia Basal Ganglia Syndrome: A Combined Western-Korean Medicine Approach
See the Original "".

Abstract

Objectives:

The purpose of this report is to introduce a rare case of a patient with Chorea Hyperglycemia Basal Ganglia syndrome (C-H-BG) whose initial medical interventions were started 2 weeks after the onset and to suggest the possibility of treatment using a combined Western-Korean medicine approach.

Methods:

A 75-year-old female C-H-BG patient complaining of persistent right-sided hemichorea was treated with a therapy that combined Korean and Western medicine from April 4, 2015 to April 29, 2015. Improvements of symptoms were measured by a motor assessment of Unified Huntington’s Disease Rating Scale (UHDRS), Visual Analog Scale (VAS) and the number of involuntary movements.

Results:

Motor assessment of UHDRS, VAS and the number of involuntary movements all showed a gradually improving tendency during 26 days of admission treatment. However, the patient’s hemichorea persisted.

Conclusion:

Rapid blood sugar control is the most important treatment for C-H-BG because pathologic changes of basal ganglia seem to become irreversible as time goes by. A combined Western-Korean medicine approach to treating C-H-BG seems effective not only in reducing hemichorea, but also in the management of accompanying symptoms such as muscle pain and general weakness.

Fig. 1
T1 weighted brain MRI image
*High signal intensity lesion at left putamen.
acup-33-1-117f1.gif
Fig. 2
Changes of UHDRS-motor assessment
acup-33-1-117f2.gif
Fig. 3
Changes of VAS
acup-33-1-117f3.gif
Fig. 4
Changes of the number of involuntary movements of right lower extremity for 30 minutes
acup-33-1-117f4.gif
IV.
IV.

References

1. Ahmad A, Paliwal P, Wakerley BR. Vascular contribution to hyperglycaemia-induced hemichorea. Diab Vasc Dis Res. 2013;10(4):378–9.
crossref pmid
2. Lee BC, Hwang SH, Chang GY. Hemiballismus-hemichorea in older diabetic women: a clinical syndrome with MRI correlation. Neurology. 1999;52(3):646–8.
crossref pmid
3. Guisado R, Arieff AI. Neurological manifestations of diabetic comas: correlation with biochemical alterations in the brain. Metabolism. 1975;24(5):665–79.
crossref pmid
4. Oh SH, Lee KY, Im JH, Lee MS. Chorea associated with non-ketotic hyperglycemia and hyperintensity basal ganglia lesiononT1-weighted brain MRI study: a meta-analysis of 53 cases including four present cases. J Neurol Sci. 2002;200(1–2):57–62.
crossref pmid
5. Ohara S, Nakagawa S, Tabata K, Hashimoto T. Hemiballism with hyperglycemia and striatal T1-MRI hyperintensity: an autopsy report. Mov Disord. 2001;16(3):521–5.
crossref pmid
6. Shan DE, Ho DM, Chang C, Pan HC, Teng MM. Hemichorea–hemiballism: an explanation for MR signal changes. Am J Neuroradiol. 1998;19(5):863–70.
pmid
7. Fujioka M, Taoka T, Matsuo Y, Hiramatsu KI, Sakaki T. Novel brain ischemic change on MRI: delayed ischemic hyperintensity on T1-weighted images and selective neuronal death in the caudoputamen of rats after brief focal ischemia. Stroke. 1999;30(5):1043–6.
crossref pmid
8. Danve A, Kulkarni S, Bhoite G. Non-ketotic hyperglycemia unmasks hemichorea. J Community Hosp Intern Med Perspect. 2015;5(4):1–5.
crossref
9. Hyun WC, Lee SR. Studies on the Effect of AntiConvulsion and Analgesic by Ukgansan and Ukgansangami. J of Oriental Neuropsychiatry. 1994;5(1):69–79.

10. Kim KS, Sung GK, Moon BS. An Experimental Study on the Antiepileptic Effects of Ukgansan. KIMS. 1998;19(1):57–72.

11. Satoh T, Takahashi T, Iwasaki K, et al. Traditional Chinese Medicine on four patients with Huntington’s disease. Mov Disord. 2009;24(3):453–5.
crossref pmid
12. Kim WH, Choi DY. Bowels-viscera syndrome differentiation and treatment. Seoul: Seongbosa. 1985:161–2.

13. Kim JW, Hyun JO, Paik JW, et al. Clinical Observation on 1 Case Patient of The Myoclunus and Hemiparesis caused by The Pons Infarction. Journal of KIOM. 2004;10(2):17–25.



Article and Issues
For this Journal
For Authors
Ethics
Submit Manuscript
Editorial Office
Gil Korean Medical Hospital, Gachon University
Keunumul-Ro, Chung-Ku, Inchoen 22138, Korea
Tel: +82-70-7606-6353,4    Fax: +82-32-232-3334    E-mail: jared@e-jar.org                

Copyright © 2020 by Korean Acupuncture & Moxibustion Medicine Society. All rights reserved.

Developed in M2community

Close layer
prev next