A Comparative Study of the Effects of Jungsongouhyul Pharmacopuncture Treatment and Bee Venom Pharmacopuncture Treatment on Peripheral Facial Paralysis

Article information

Acupunct. 2014;31(2):135-144
Publication date (electronic) : 2014 June 20
doi : https://doi.org/10.13045/acupunct.2014031
Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Kyung Hee University
*Corresponding author : Department of Acupuncture & Moxibustion Medicine, Kangnam Korean Hospital Kyung Hee University, 225, Yeongdong-daero, Gangnam-gu, Seoul, 135-501, Republic of Korea, Tel : +82-2-3457-9014 E-mail : ackys@hanmail.net
Received 2014 February 11; Revised 2014 May 09; Accepted 2014 May 21.

Abstract

Objectives:

This study was designed to compare the effects of Jungsongouhyul pharmacopuncture treatment with bee venom pharmacopuncture treatment in hospitalized patients with peripheral facial paralysis

Methods:

This study was done on a total of 41 patients with peripheral facial paralysis who were admitted into the Korean Medicine Hospital from February 1st, 2013 to April 30th, 2014. Wedivided patients into two groups. The Jungsongouhyul group was treated by Jungsongouhyul pharmacopuncture once a day and the bee venom group was treated by bee venom pharmacopuncture once a day. To compare the therapeutical effects of the two treatments, we used Yanagihara’s unweighted grading system, House-Brachmann grading system, lip-length & snout indices and facial disablity index twice - before initial treatment and after final treatment.

Results:

Both Yanagihara’s score and House-Brachmann grading system score improved in each group. However, there were no significant differences in improvement between the bee venom group and the Jungsongouhyul group.

Conclusions:

Jungsongouhyul pharmacopuncture treatment appears to be as effective as bee venom pharmacopuncture treatment to improve symptoms of peripheral facial paralysis.

Y-System

H-B Grade

General Characteristics

The Changes of Scale Score between before Treatment and after Final Treatment in Jungsongouhyul Group

The Changes of Scale Score between before Treatment and after Final Treatment in BV Group

Comparison of Scale Score before Treatment between Jungsongouhyul Group and BV Group

Comparison of Scale Score after Final Treatment between Jungsongouhyul Group and BV Group

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Article information Continued

Table 1.

Y-System

Scale of rating
At rest 0 1 2 3 4
Wrinkle forehead 0 1 2 3 4
Blink 0 1 2 3 4
Closure of eye tightly 0 1 2 3 4
Closure of eye lightly 0 1 2 3 4
Closure of eye on involved side only 0 1 2 3 4
Wrinkle nose 0 1 2 3 4
Whistle 0 1 2 3 4
Grin 0 1 2 3 4
Depress lower lip 0 1 2 3 4

Table 2.

H-B Grade

Grade Description Characteristics
I Normal Normal facial function all areas

II Mild dysfunction Gross : Slight weakness noticeable on close inspection may have very slight synkinesis
At rest : Normal symmetry and tone
Motion
  Forehead : Moderate to good function
  Eye : complete closure with minimum effort
  Mouth : Slight asymmetry

III Moderate dysfunction Gross : obvious but not disfiguring difference between two sides, noticeable but not severe synkinesis, contracture, and/or hemifacial spasm
At rest : normal symmetry and tone
Motion
  Forehead : slight to moderate movement
  Eye : complete closure with effort
  Mouth : slightly weak with maximum effort

IV Moderately severe dysfunction Gross : obvious weakness and/or disfiguring asymmetry
At rest : normal symmetry and tone
Motion
  Forehead : none
  Eye : incomplete closure
  Mouth : asymmetric with maximum effort

V Severe dysfunction Gross : only barely perceptible
At rest : asymmetry
Motion
  Forehead : none
  Eye : incomplete closure
  Mouth : slight movement

VI Total paralysis No movement

Table 3.

General Characteristics

Jungsongouhyul group(n=21) BV group(n=20) p-value
Sex(male/female) 21(9/12) 20(10/10)
Age 41.95±13.13(23∼69) 47.10±12.07(15∼65) 0.137*
Left/right 11/10 8/12
Period of onset to first hospital visit 7.43±5.36(2∼21) 10.80±6.92(1∼30) 0.105*
Hospitalization period 11.86±1.65(9∼15) 12.05±1.82(8∼14) 0.560*
Past history of facial palsy 5 1 0.184**
Steroid intake 13 16 0.306**
DM 4 2 0.663**

BV : bee venom.

DM : diabetes mellitus.

*

calculated by Mann-Whitney U test, p >0.05.

**

calculated by Fisher’s exact test, p >0.05.

Table 4.

The Changes of Scale Score between before Treatment and after Final Treatment in Jungsongouhyul Group

Before treatment After treatment p-value
Y-score 11.52±3.86 19.28±7.46 0.001*
H-B grade 3.57±0.51 2.81±0.75 0.001
Lip-length 14.66±6.71 22.10±7.63 0.001*
Snout 17.96±5.59 23.09±5.74 0.001*
FDI 126.24±27.65 159.95±19.79 0.001*

Y-score : Yanagihara’s score.

H-B grade : House-Brackmann grade.

FDI : facial disablilty index.

*

p-value<0.05 by Wilcoxon’s signed-rank test.

Table 5.

The Changes of Scale Score between before Treatment and after Final Treatment in BV Group

Before treatment After treatment p-value
Y-score 9.35±3.15 15.80±6.03 0.001*
H-B grade 3.85±0.59 3.20±0.70 0.001*
Lip-length 11.84±6.51 20.10±9.82 0.001*
Snout 15.34±4.37 19.64±4.50 0.001*
FDI 127.65±27.61 152.90±20.12 0.001*

Y-score : Yanagihara’s score.

H-B grade : House-Brackmann grade.

FDI : facial disablilty index.

*

p-value<0.05 by Wilcoxon’s signed-rank test.

Table 6.

Comparison of Scale Score before Treatment between Jungsongouhyul Group and BV Group

Jungsongouhyul group BV group p-value
Y-B 11.52±3.86 9.35±3.15 0.053*
HB-B 3.57±0.51 3.85±0.59 0.132*
LL-B 14.66±6.71 11.84±6.51 0.188*
S-B 17.96±5.59 15.34±4.37 0.230*
FDI-B 126.24±27.65 127.65±27.61 0.686*
*

calculated by Mann-Whitney U test, p >0.05.

Y-B : Y-score of before treatment.

HB-B : H-B grade of before treatment.

LL-B : LL of before treatment.

S-B : S of before treatment.

FDI-B : FDI of before treatment.

Table 7.

Comparison of Scale Score after Final Treatment between Jungsongouhyul Group and BV Group

Jungsongouhyul group BV group p-value
Y-A 19.28±7.46 15.80±6.03 0.065*
HB-A 2.81±0.75 3.20±0.70 0.092*
LL-A 22.10±7.63 20.10±9.82 0.465*
S-A 23.09±5.74 19.64±4.50 0.052*
FDI-A 159.95±19.79 152.90±20.12 0.389*
*

calculated by Mann-Whitney U test, p >0.05.

Y-A : Y-score of after final treatment.

HB-A : H-B grade of after final treatment.

LL-A : lip-length of after final treatment.

S-A : snout of after final treatment.

FDI-A : FDI of after final treatment.