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J Acupunct Res > Volume 30(2); 2013 > Article
Published online April 21, 2013.
DOI: https://doi.org/10.13045/kamms.2013013   
Review on Clinical Trials of Chemotherapy Induced Toxicity with Acupuncture in PubMed Database
Jong Yoon Kim, Jin Youp Kim, Nam Sik Kim, So Jung Kim, Munkhgerel Oyungerel, Yong Suk Kim, Do Young Choi, Sang Soo Nam
Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Kyung Hee University
*Corresponding author.
Sang Soo Nam
Tel: +82-2-3457-9011   Email: dangun66@gmail.com
Abstract
Objectives : The purpose of this study is to review of Clinical trials related to the treatment of chemotherapy induced-toxicity by acupuncture therapy.

Methods :
We searched PubMed by using word of "chemotherapy induced, acupuncture" (Limits : Full text available, 10 years, Clinical trials, Humans, English). We analyzed 15 research paper and examined published journals, years, countries, topic, study design, their results, interventions, participants and instruments of assessment.

Results :
Eleven journals with fifteen papers were searched. These papers were published in USA, Germany, etc. On the topic of these clinical trials, seven of them were about nausea(vomiting), two about peripheral neuropathy, two about hot flash, two about arthralgia and one about neutropenia, one about fatigue. Six of these studies were single blinded, randomized controlled trial. Twelve studies reported significant effect. The median for number of final participants was 35.5 persons. Assessment for outcomes were versatile questionnaire, nerve conduction studies, WBC, ANC, G-CSF examination, etc.

Conclusions :
Their median for impact factor was 3.650 and average modified Jadad score of six RCTs was 4.33. In order to provide appropriate evidence regarding the effectiveness of acupuncture in treatment for chemotherapy-induced toxicity, more rigorous and well-designed studies are necessary.
Keywords: Chemotherpy induced; Clinical trials; Acupuncture; PubMed
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